How Bone Cancer is Diagnosed and Treated

Bone cancer, though relatively rare, is a serious and potentially life-threatening condition that requires prompt diagnosis and treatment. The most common form of bone cancer in children and young adults is osteosarcoma, a tumor that typically develops in the long bones of the body, like the arms and legs. Understanding the diagnosis, available treatments, and advancements in cancer therapies is crucial for both patients and their families.
At Pi Health Cancer Hospital, under the expert guidance of Dr. Venugopal Arroju, Clinical Director and Senior Consultant in Medical Oncology & Hemato-Oncology, significant strides are being made in the treatment and clinical research of bone cancer. This blog will cover how bone cancer is diagnosed and treated, focusing on osteosarcoma and the cutting-edge clinical trials conducted at Pi Health Cancer Hospital to push the boundaries of cancer therapies.
What is Bone Cancer?
Bone cancer refers to a type of cancer that originates in the bone tissue. Unlike metastatic bone cancer, which results from cancer spreading from other organs (like breast or lung cancer), primary bone cancer begins directly in the bones. The most common types of bone cancer include osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. Osteosarcoma is particularly prevalent among children and young adults, often occurring in the arms, legs, and pelvis.
Early Symptoms of Bone Cancer
Recognizing bone cancer early is vital for successful treatment. The early symptoms of bone cancer may vary depending on the tumor’s location, but common signs to watch out for include:
- Pain in the bones or joints that worsens over time.
- Swelling or lumps near the affected area.
- Fractures in the bone, especially with minimal trauma.
- Fatigue, weight loss, or fever in some cases.
- Numbness or tingling in the affected area, particularly if the tumor is pressing on nerves.
How is Bone Cancer Diagnosed?
Once diagnosed, bone cancer treatment typically involves a combination of surgery, chemotherapy, and radiation therapy. The specific treatment plan will depend on the type, location, and stage of the tumor.
- Surgery
Surgery is often the primary treatment for osteosarcoma and other bone cancers. The goal is to remove the tumor entirely while preserving as much healthy tissue as possible. In some cases, limb-sparing surgery can be performed, but if the tumor is too large or affects the function of the limb, amputation may be necessary.
- Chemotherapy
Chemotherapy uses drugs to kill cancer cells or stop their growth. It is often used in combination with surgery, especially in osteosarcoma, to shrink tumors before surgery or to kill any remaining cancer cells after surgery. Chemotherapy can be delivered orally or through an intravenous (IV) line.
- Radiation Therapy
Radiation therapy may be used in cases where surgery is not possible or to target cancer cells that may have spread to nearby areas. It uses high-energy rays to destroy cancer cells or shrink tumors.
- Targeted Therapy and Immunotherapy
In addition to traditional treatments, targeted therapies and immunotherapy are emerging as promising options for treating bone cancer. Targeted therapies aim to interfere with specific molecules involved in the growth and spread of cancer cells, while immunotherapy enhances the body’s immune system to recognize and destroy cancer cells.
Bone Cancer Treatment: Current Approaches
Chemotherapy is one of the most widely used treatments for ovarian cancer, especially in advanced stages. It involves the use of powerful drugs to kill cancer cells or stop their growth. Chemotherapy is often used after surgery to eliminate any remaining cancer cells.
- Intraperitoneal Chemotherapy: This treatment involves administering chemotherapy directly into the abdominal cavity, allowing the drugs to target cancer cells in the peritoneal cavity, where ovarian cancer commonly spreads.
- Systemic Chemotherapy: This is the most common form of chemotherapy, where drugs are delivered through the bloodstream to reach cancer cells throughout the body.
At PI Health Cancer Hospital, chemotherapy is personalized based on the patient’s specific needs, ensuring the most effective treatment with minimal side effects. The hospital is known for its compassionate care and innovative methods that reduce chemotherapy-related side effects.
Conclusion
Bone cancer, especially osteosarcoma, is a serious condition that requires early detection and prompt, effective treatment. With the groundbreaking clinical trials being conducted at Pi Health Cancer Hospital, patients have access to the latest cancer therapies and treatments, significantly improving their chances for recovery and long-term survival. For more information on bone cancer treatment, osteosarcoma, and cancer therapies, or to learn about the clinical trials available, visit Pi Health Cancer Hospital.
By staying informed and proactive about bone cancer, we can help ensure better outcomes for patients and contribute to the ongoing advancements in cancer research.
FAQS
The survival rate for osteosarcoma varies depending on the stage at diagnosis and the success of the treatment. With early detection and advanced treatment options, the survival rate has significantly improved in recent years.
While bone cancer cannot be prevented, maintaining a healthy lifestyle and minimizing exposure to harmful substances (like tobacco and radiation) may lower the risk.
Bone cancer is a primary cancer that originates in the bone, while metastatic bone cancer occurs when cancer from another part of the body, such as breast or prostate cancer, spreads to the bone.
Advancements in bone cancer treatment include immunotherapy, gene therapy, and targeted therapies, which offer more personalized and effective approaches to treatment.
Treatment duration varies depending on the type and stage of the cancer. Chemotherapy cycles can take several months, while surgery and radiation therapy may require a few weeks of recovery.
Common side effects of ovarian cancer treatments include fatigue, nausea, hair loss, and weakened immune function. However, personalized care at PI Health Cancer Hospital ensures that these side effects are minimized.

Dr. A. Venugopal
Clinical Director & HOD Medical Oncology Senior Consultant Medical Oncologist & Hemato-Oncologist
About Author
Dr. A. Venugopal
MD (General Medicine), DM (Medical Oncology), MRCP – SCE Medical Oncology (UK), ECMO (Switzerland).
Dr A. Venugopal is One of the best medical oncologist and Hemato Oncologist in hyderabad, currently serving as the Head of the Department and Senior Medical Oncologist, Hemato Oncologist at Pi Health Cancer Hospital in Gachibowli, Hyderabad. He brings over 15 years of extensive experience in the field of Oncology.